FBXO22 抗体 (AA 182-232)
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北京 101111
Quick Overview for FBXO22 抗体 (AA 182-232) (ABIN8121356)
抗原
See all FBXO22 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 182-232
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原理
- FBX22 Antibody
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特异性
- This antibody detects endogenous levels of FBX22 at Human/Mouse
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human FBX22 AA range: 182-232
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亚型
- IgG
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应用备注
- WB 1:500-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- FBXO22 (F-Box Protein 22 (FBXO22))
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别名
- FBX22
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背景
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Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010],
Gene Name: FBXO22 FBX22
Protein Name: FBX22
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基因ID
- 26263
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UniProt
- Q8NEZ5
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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