EIF6 抗体 (pSer235)
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Quick Overview for EIF6 抗体 (pSer235) (ABIN8121324)
抗原
See all EIF6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer235
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原理
- EIF6 (Phospho Ser235) Antibody
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特异性
- This antibody detects endogenous levels of EIF6 (Phospho-Ser235) at Human, Mouse,Rat
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human EIF6 (Phospho-Ser235)
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亚型
- IgG
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应用备注
- WB 1:500-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))
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别名
- EIF6
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背景
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Synonyms: Eukaryotic translation initiation factor 6 (eIF-6) (B(2)GCN homolog) (B4 integrin interactor) (CAB) (p27(BBP))
Background: Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains.The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2012],
Gene Name: EIF6 EIF3A ITGB4BP OK/SW-cl.27
Protein Name: EIF6 (Phospho-Ser235)
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基因ID
- 3692
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UniProt
- P56537
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途径
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
抗原
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