ERN1 抗体
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北京 101111
Quick Overview for ERN1 抗体 (ABIN8121178)
抗原
See all ERN1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- IRE1α Antibody
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特异性
- IRE1α Antibody detects endogenous levels of IRE1α protein.
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纯化方法
- Affinity purification
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免疫原
- Purified recombinant fragment of human IRE1alpha (aa282-433) expressed in E. Coli.
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
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别名
- IRE1alpha
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背景
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Synonyms: ERN1, IRE1, Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, Inositol-requiring protein 1, hIRE1p, Ire1-alpha, IRE1a
Background: The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq, Jul 2008],
Gene Name: ERN1
Protein Name: Serine/threonine-protein kinase/endoribonuclease IRE1
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基因ID
- 2081
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UniProt
- O75460
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途径
- ER-Nucleus Signaling, Unfolded Protein Response
抗原
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