EEA1 抗体
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北京 101111
Quick Overview for EEA1 抗体 (ABIN8121126)
抗原
See all EEA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- EEA1 Rabbit mAb
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特异性
- This antibody detects endogenous levels of EEA1 protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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应用备注
- WB, 1:1000-1:5000 | IHC, 1:100-1:200 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- EEA1 (Early Endosome Antigen 1 (EEA1))
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别名
- EEA1
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背景
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Synonyms: EEA1, ZFYVE2, Early endosome antigen 1, Endosome-associated protein p162, Zinc finger FYVE domain-containing protein 2
Background: disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases. , domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate. , function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. , similarity:Contains 1 C2H2-type zinc finger. , similarity:Contains 1 FYVE-type zinc finger. , subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding. ,
Gene Name: EEA1
Protein Name: EEA1
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基因ID
- 8411
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UniProt
- Q15075
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途径
- Toll-Like Receptors Cascades
抗原
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