E2F2 抗体 (acLys122)
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北京 101111
Quick Overview for E2F2 抗体 (acLys122) (ABIN8121110)
抗原
See all E2F2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- acLys122
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原理
- E2F-2 (Acetyl Lys122) Antibody
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特异性
- This antibody detects endogenous levels of Human,Mouse E2F-2 (Acetyl Lys122)
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human E2F-2 (Acetyl Lys122)
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亚型
- IgG
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anti-E2F Transcription Factor 2 (E2F2) (AA 1-83) antibody
E2F2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 2 (E2F2) antibodyE2F2 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB5250 unconjugated Recombinant Antibody
anti-E2F Transcription Factor 2 (E2F2) (AA 1-437) antibodyE2F2 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 2 (E2F2) (AA 258-286) antibodyE2F2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB27633 unconjugated
anti-E2F Transcription Factor 2 (E2F2) (AA 191-240) antibodyE2F2 适用: 人, 小鼠, 兔, 犬, Cow, 马, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 2 (E2F2) (Internal Region) antibodyE2F2 适用: 人, 小鼠 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 2 (E2F2) (C-Term) antibodyE2F2 适用: 人, 小鼠, 兔, 犬, 马, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 2 (E2F2) antibodyE2F2 适用: 人 DB 宿主: 小鼠 Monoclonal 2302C4a unconjugated
anti-E2F Transcription Factor 2 (E2F2) antibodyE2F2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-E2F Transcription Factor 2 (E2F2) (Internal Region) antibodyE2F2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- E2F2 (E2F Transcription Factor 2 (E2F2))
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别名
- E2F-2
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背景
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Synonyms: Transcription factor E2F2 (E2F-2)
Background: function:Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F-2 binds specifically to RB1 protein, in a cell-cycle dependent manner.,PTM:Phosphorylated by CDK2 and cyclin A-CDK2 in the S-phase.,similarity:Belongs to the E2F/DP family.,subunit:Component of the DRTF1/E2F transcription factor complex. Forms heterodimers with DP family members. The E2F-2 complex binds specifically hypophosphorylated retinoblastoma protein RB1. During the cell cycle, RB1 becomes phosphorylated in mid-to-late G1 phase, detaches from the DRTF1/E2F complex, rendering E2F transcriptionally active. Viral oncoproteins, notably E1A, T-antigen and HPV E7, are capable of sequestering RB protein, thus releasing the active complex. Binds EAPP.,tissue specificity:Highest level of expression is found in placenta, low levels are found in lung. Found as well in many immortalized cell lines derived from tumor samples.,
Gene Name: E2F2
Protein Name: E2F-2 (Acetyl Lys122)
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基因ID
- 1870
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UniProt
- Q14209
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication
抗原
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