Doublecortin 抗体
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北京 101111
Quick Overview for Doublecortin 抗体 (ABIN8121062)
抗原
See all Doublecortin (DCX) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Doublecortin Rabbit mAb
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特异性
- This antibody detects endogenous levels of Neuronal migration protein doublecortin protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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anti-Doublecortin (DCX) (AA 362-411) antibody
DCX 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 2G5 unconjugated
anti-Doublecortin (DCX) (AA 232-242) antibodyVerified DCX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Doublecortin (DCX) (AA 362-411) antibodyDCX 适用: 人 WB, ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Doublecortin (DCX) (AA 69-81) antibodyVerified DCX 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Doublecortin (DCX) (AA 200-250) antibodyDCX 适用: 人, 小鼠 WB, IHC, ICC, IP 宿主: 兔 Monoclonal BLR168J unconjugated Recombinant Antibody
anti-Doublecortin (DCX) (AA 1-360) antibodyDCX 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 1G12 unconjugated
anti-Doublecortin (DCX) (AA 11-360) antibodyDCX 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin (DCX) (AA 108-360) antibodyDCX 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin (DCX) (AA 107-137) antibodyDCX 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB15193 unconjugated
anti-Doublecortin (DCX) (pSer335) antibodyDCX 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB, 1:2000-1:10000 | IHC, 1:50-1:200 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- Doublecortin (DCX)
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别名
- Doublecortin
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背景
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Synonyms: DCX,DBCN,LISX,Neuronal migration protein doublecortin,Doublin,Lissencephalin-X,Lis-X
Background: This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, cognitive disability, subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain" syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]
Gene Name: DCX
Protein Name: Neuronal migration protein doublecortin
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基因ID
- 1641
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UniProt
- O43602
抗原
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