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Doublecortin 抗体 (pSer378)

The 兔 多克隆 anti-Doublecortin antibody (ABIN8121061) specifically detects Doublecortin in WB, IHC 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8121061
发货至: 中国
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Quick Overview for Doublecortin 抗体 (pSer378) (ABIN8121061)

抗原

See all Doublecortin (DCX) 抗体
Doublecortin (DCX)

适用

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人, 小鼠, 大鼠

宿主

  • 112
  • 11
  • 4
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兔

克隆类型

  • 97
  • 32
多克隆

标记

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This Doublecortin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    pSer378

    原理

    Doublecortin (Phospho Ser378) Antibody

    特异性

    This antibody detects endogenous phospho levels of Doublecortin (Phospho-Ser378) at Human:S378, Mouse:S297, Rat:S297

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

    免疫原

    Synthesized peptide derived from human Doublecortin (Phospho-Ser378)

    亚型

    IgG
  • 应用备注

    IHC 1:50-200, WB 1:500-2000. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Doublecortin (DCX)

    别名

    Doublecortin

    背景

    Synonyms: Neuronal migration protein doublecortin (Doublin; Lissencephalin-X; Lis-X)

    Background: This gene encodes a member of the doublecortin family.The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain&quo

    Gene Name: DCX DBCN LISX

    Protein Name: Doublecortin (Phospho-Ser378)

    基因ID

    1641

    UniProt

    O43602
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