Doublecortin 抗体 (pSer297)
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Quick Overview for Doublecortin 抗体 (pSer297) (ABIN8121060)
抗原
See all Doublecortin (DCX) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer297
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原理
- Doublecortin (Phospho Ser297) Antibody
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特异性
- This antibody detects endogenous levels of Human Rat Doublecortin (phospho-Ser297)
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized phosho peptide around human Doublecortin (Ser297)
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亚型
- IgG
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应用备注
- WB 1:1000-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Doublecortin (DCX)
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别名
- Doublecortin
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背景
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Synonyms: Neuronal migration protein doublecortin (Doublin) (Lissencephalin-X) (Lis-X)
Background: This gene encodes a member of the doublecortin family.The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain&quo
Gene Name: DCX DBCN LISX
Protein Name: Doublecortin (Ser297)
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基因ID
- 1641
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UniProt
- O43602
抗原
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