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Desmoglein 1 抗体 (AA 30-90)

This 兔 多克隆 antibody specifically detects Desmoglein 1 in WB, IHC, IF 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8120972
发货至: 中国
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Quick Overview for Desmoglein 1 抗体 (AA 30-90) (ABIN8120972)

抗原

See all Desmoglein 1 (DSG1) 抗体
Desmoglein 1 (DSG1)

适用

  • 128
  • 34
  • 23
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 76
  • 52
  • 1
兔

克隆类型

  • 72
  • 57
多克隆

标记

  • 58
  • 11
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This Desmoglein 1 antibody is un-conjugated

应用范围

  • 63
  • 56
  • 39
  • 22
  • 20
  • 13
  • 11
  • 9
  • 4
  • 4
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
  • 抗原表位

    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-90

    原理

    Dsg1 Antibody

    特异性

    The antibody detects endogenous Dsg1

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthetic peptide from human protein at AA range: 30-90

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,IHC 1:500-200, ELISA 1:10000-20000. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Desmoglein 1 (DSG1)

    别名

    Dsg1

    背景

    Synonyms: Desmoglein-1 (Cadherin family member 4, Desmosomal glycoprotein 1, DG1, DGI, Pemphigus foliaceus antigen)

    Background: This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015],

    Gene Name: DSG1 CDHF4

    Protein Name: Desmoglein-1 (Cadherin family member 4) (Desmosomal glycoprotein 1) (DG1) (DGI) (Pemphigus foliaceus antigen)

    基因ID

    1828

    UniProt

    Q02413

    途径

    Cell-Cell Junction Organization
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