Desmoglein 1 抗体 (AA 30-90)
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北京 101111
Quick Overview for Desmoglein 1 抗体 (AA 30-90) (ABIN8120972)
抗原
See all Desmoglein 1 (DSG1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-90
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原理
- Dsg1 Antibody
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特异性
- The antibody detects endogenous Dsg1
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthetic peptide from human protein at AA range: 30-90
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:500-200, ELISA 1:10000-20000. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Desmoglein 1 (DSG1)
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别名
- Dsg1
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背景
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Synonyms: Desmoglein-1 (Cadherin family member 4, Desmosomal glycoprotein 1, DG1, DGI, Pemphigus foliaceus antigen)
Background: This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015],
Gene Name: DSG1 CDHF4
Protein Name: Desmoglein-1 (Cadherin family member 4) (Desmosomal glycoprotein 1) (DG1) (DGI) (Pemphigus foliaceus antigen)
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基因ID
- 1828
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UniProt
- Q02413
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途径
- Cell-Cell Junction Organization
抗原
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