Desmocollin 1 抗体 (AA 749-799)
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Quick Overview for Desmocollin 1 抗体 (AA 749-799) (ABIN8120970)
抗原
See all Desmocollin 1 (DSC1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 749-799
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原理
- DSC1 Antibody
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特异性
- This antibody detects endogenous levels of DSC1 at Human/Mouse
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human DSC1 AA range: 749-799
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亚型
- IgG
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应用备注
- WB 1:500-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Desmocollin 1 (DSC1)
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别名
- DSC1
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背景
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Background: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus, a life-threatening autoimmune disease, is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein. [provided by RefSeq, Nov 2015],
Gene Name: DSC1 CDHF1
Protein Name: DSC1
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基因ID
- 1823
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UniProt
- Q08554
抗原
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