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Desmocollin 1 抗体 (AA 749-799)

The 兔 多克隆 anti-Desmocollin 1 antibody is suitable to detect Desmocollin 1 in samples from 人 和 小鼠. It has been validated for WB.
产品编号 ABIN8120970
发货至: 中国
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Quick Overview for Desmocollin 1 抗体 (AA 749-799) (ABIN8120970)

抗原

See all Desmocollin 1 (DSC1) 抗体
Desmocollin 1 (DSC1)

适用

  • 39
  • 9
  • 4
人, 小鼠

宿主

  • 38
  • 3
  • 1
兔

克隆类型

  • 35
  • 7
多克隆

标记

  • 28
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Desmocollin 1 antibody is un-conjugated

应用范围

  • 31
  • 15
  • 14
  • 7
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 10
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 749-799

    原理

    DSC1 Antibody

    特异性

    This antibody detects endogenous levels of DSC1 at Human/Mouse

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human DSC1 AA range: 749-799

    亚型

    IgG
  • 应用备注

    WB 1:500-2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Desmocollin 1 (DSC1)

    别名

    DSC1

    背景

    Background: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus, a life-threatening autoimmune disease, is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein. [provided by RefSeq, Nov 2015],

    Gene Name: DSC1 CDHF1

    Protein Name: DSC1

    基因ID

    1823

    UniProt

    Q08554
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