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CYFIP1 抗体 (AA 980-1060)

The 兔 多克隆 anti-CYFIP1 antibody is suitable to detect CYFIP1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN8120892
发货至: 中国
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Quick Overview for CYFIP1 抗体 (AA 980-1060) (ABIN8120892)

抗原

See all CYFIP1 抗体
CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))

适用

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人, 小鼠, 大鼠

宿主

  • 28
兔

克隆类型

  • 22
  • 6
多克隆

标记

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This CYFIP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

    • 4
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    AA 980-1060

    原理

    CYFP1 Antibody

    特异性

    CYFP1 Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human protein . at AA range: 980-1060

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))

    别名

    CYFP1

    背景

    Background: function:Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth. Binds to F-actin but not to RNA.,similarity:Belongs to the CYFIP family.,subcellular location:Highly expressed in the perinuclear region. Enriched in synaptosomes, membrane ruffles and at the tips of lamellipodia.,subunit:Interacts with the active GTP-bound form of RAC1. Interacts with FMR1/FMRP but does not bind to related proteins FXR1 or FXR2. Component of the WAVE2 complex composed of ABI1, CYFIP1/SRA1, NCKAP1/NAP1 and WASF2/WAVE2 (By similarity). Interacts through its C-terminus with the C-terminus of DPYSL2/CRMP2 which is necessary for DPYSL2-induced axon outgrowth.,

    Gene Name: CYFIP1 KIAA0068

    Protein Name: Cytoplasmic FMR1-interacting protein 1 (Specifically Rac1-associated protein 1) (Sra-1) (p140sra-1)

    基因ID

    23191

    UniProt

    Q7L576
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