CSTB 抗体 (AA 20-60)
Our Local Distributor
北京 101111
Quick Overview for CSTB 抗体 (AA 20-60) (ABIN8120843)
抗原
See all CSTB 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 20-60
-
原理
- Cystatin B Antibody
-
特异性
- The antibody detects endogenous Cystatin B
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthetic peptide from human protein at AA range: 20-60
-
亚型
- IgG
-
-
-
-
应用备注
- IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- CSTB (Cystatin B (Stefin B) (CSTB))
-
别名
- Cystatin B
-
背景
-
Synonyms: Cystatin-B (CPI-B, Liver thiol proteinase inhibitor, Stefin-B)
Background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens.This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). One type of mutation responsible for EPM1 is the expansion in the promoter region of this gene of a CCCCGCCCCGCG rep
Gene Name: CSTB CST6 STFB
Protein Name: Cystatin-B (CPI-B) (Liver thiol proteinase inhibitor) (Stefin-B)
-
基因ID
- 1476
-
UniProt
- P04080
-
途径
- Response to Water Deprivation
抗原
-