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CDKN1C 抗体 (AA 200-316)

The 兔 单克隆 anti-CDKN1C antibody is suitable to detect CDKN1C in samples from 人. It has been validated for IHC.
产品编号 ABIN8120826
发货至: 中国
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Quick Overview for CDKN1C 抗体 (AA 200-316) (ABIN8120826)

抗原

See all CDKN1C 抗体
CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

适用

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人

宿主

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兔

克隆类型

  • 89
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单克隆

标记

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This CDKN1C antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

AB1475
  • 抗原表位

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    AA 200-316

    原理

    p57kip2 Rabbit mAb

    特异性

    This antibody detects endogenous levels of p57kip2 (ABT76R) rabbit mAb protein.

    纯化方法

    The antibody was purified by protein A affinity chromatography.

    免疫原

    A synthetic peptide corresponding to the amino acid region 200 - 316 of the human p57kip2.

    亚型

    IgG
  • 应用备注

    WB, 1:500-1:2000 | IHC, 1:50-1:200 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

    别名

    p57kip2

    背景

    Synonyms: CDKN1C, KIP2, Cyclin-dependent kinase inhibitor 1C, Cyclin-dependent kinase inhibitor p57, p57Kip2

    Background: This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

    Gene Name: CDKN1C

    Protein Name: p57kip2 (ABT76R) rabbit mAb

    基因ID

    1028

    UniProt

    P49918

    途径

    Cell Division Cycle, Dopaminergic Neurogenesis
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