CDKN1C 抗体 (AA 200-316)
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北京 101111
Quick Overview for CDKN1C 抗体 (AA 200-316) (ABIN8120826)
抗原
See all CDKN1C 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 200-316
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原理
- p57kip2 Rabbit mAb
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特异性
- This antibody detects endogenous levels of p57kip2 (ABT76R) rabbit mAb protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- A synthetic peptide corresponding to the amino acid region 200 - 316 of the human p57kip2.
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亚型
- IgG
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应用备注
- WB, 1:500-1:2000 | IHC, 1:50-1:200 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
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别名
- p57kip2
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背景
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Synonyms: CDKN1C, KIP2, Cyclin-dependent kinase inhibitor 1C, Cyclin-dependent kinase inhibitor p57, p57Kip2
Background: This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Gene Name: CDKN1C
Protein Name: p57kip2 (ABT76R) rabbit mAb
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基因ID
- 1028
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UniProt
- P49918
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途径
- Cell Division Cycle, Dopaminergic Neurogenesis
抗原
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