CDKN1C 抗体 (AA 200-316)
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北京 101111
Quick Overview for CDKN1C 抗体 (AA 200-316) (ABIN8120824)
抗原
See all CDKN1C 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 200-316
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原理
- p57kip2 Rabbit mAb (Ready to Use)
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特异性
- The antibody can specifically recognize human p57kip2 protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- A synthetic peptide corresponding to the amino acid region 200 - 316 of the human p57kip2 protein.
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亚型
- IgG
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应用备注
- It has been optimized for direct use, requiring no further dilution.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze
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储存条件
- 4 °C
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储存方法
- Store at 4°C. Avoid freeze.
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- CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
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别名
- p57kip2
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背景
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Synonyms: Beckwith Wiedemann syndrome,BWCR,BWS,CDKI,CDKN 1C,CDKN1C,CDN1C_HUMAN,Cyclin dependent kinase inhibitor 1C,Cyclin dependent kinase inhibitor p57,Cyclin-dependent kinase inhibitor 1C,Cyclin-dependent kinase inhibitor p57,KIP 2,KIP2,p57,p57 Kip 2,p57KIP2,WBS
Background: P57kip2 is a cell cycle inhibitor and tumor suppressor. The gene is mainly located on the mother's chromosome 11. By blocking the G1 / S phase transition in the cell cycle, we can realize the negative regulation of the cell cycle, and then prevent cell proliferation and tumor formation. In complete hydatidiform mole, there is a lack of maternal gene and p57 negative expression, while in partial hydatidiform mole, there are genes of both parents and p57 positive expression, which can be used for the study of early hydatidiform mole pregnancy.
Gene Name: CDKN1C
Protein Name: p57kip2
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基因ID
- 1028
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UniProt
- P49918
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途径
- Cell Division Cycle, Dopaminergic Neurogenesis
抗原
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