Cullin 5 抗体 (AA 560-640)
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北京 101111
Quick Overview for Cullin 5 抗体 (AA 560-640) (ABIN8120774)
抗原
See all Cullin 5 (CUL5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 560-640
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原理
- CUL5 Antibody
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特异性
- CUL5 Polyclonal Antibody detects endogenous levels of protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human protein . at AA range: 560-640
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亚型
- IgG
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anti-Cullin 5 (CUL5) (AA 747-774), (C-Term) antibody
CUL5 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB17926 unconjugated
anti-Cullin 5 (CUL5) (AA 1-50) antibodyCUL5 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Cullin 5 (CUL5) antibodyKD Validated CUL5 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4280 unconjugated Recombinant Antibody
anti-Cullin 5 (CUL5) antibodyCUL5 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cullin 5 (CUL5) (AA 1-300) antibodyCUL5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cullin 5 (CUL5) (AA 1-300) antibodyCUL5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cullin 5 (CUL5) antibodyCUL5 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Cullin 5 (CUL5) (Internal Region) antibodyCUL5 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cullin 5 (CUL5) (AA 701-780) antibodyCUL5 适用: 人 IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cullin 5 (CUL5) antibodyCUL5 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Cullin 5 (CUL5)
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别名
- CUL5
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背景
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Background: function:Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAk2. Seems to be involved poteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.,pathway:Protein modification, protein ubiquitination.,PTM:Neddylated. Deneddylated via its interaction with the COP9 signalosome (CSN) complex.,similarity:Belongs to the cullin family.,subunit:Component of multiple ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes formed of CUL5, Elongin BC (TCEB1 and TCEB2), RBX2 and a variable SOCS box domain-containing protein as substrate-specific recognition component. Component of the probable ECS(LRRC41) complex with the substrate recognition component LRRC41. Component of the probable ECS(SOCS1) complex with the substrate recognition component SOCS1. Component of the probable ECS(WSB1) complex with the substrate recognition subunit WSB1. Component of the probable ECS(SOCS3) complex with the substrate recognition component SOCS3. Component of the probable ECS(SPSB1) complex with the substrate recognition component SPSB1. Component of the probable ECS(SPSB2) complex with the substrate recognition component SPSB2. Component of the probable ECS(SPSB4) complex with the substrate recognition component SPSB4. Component of the probable ECS(RAB40C) complex with the substrate recognition subunit RAB40C. May also form complexes containing CUL5, elongin BC complex (TCEB1 and TCEB2), RBX1 and TCEB3. May also form complexes containing CUL5, Elongin BC (TCEB1 and TCEB2), RBX1 and VHL. The substrate recognition component can also be a viral protein such as HIV Vif, or human adenovirus 5 E1B large T-antigen and E4-orf6. Interacts with RNF7/RBX2, LRRC41, SOCS3, SPSB1, SPSB2, SPSB4 and RAB40C. Interacts with ASB1, ASB2, ASB6, ASB7 and ASB12.,
Gene Name: CUL5 VACM1
Protein Name: Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1)
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基因ID
- 8065
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UniProt
- Q93034
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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