Exportin 2 抗体 (AA 1-100)
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北京 101111
Quick Overview for Exportin 2 抗体 (AA 1-100) (ABIN8120761)
抗原
See all Exportin 2 (CSE1L) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-100
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原理
- Cellular Apoptosis Susceptibility/CSE1L mouse mAb
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特异性
- This antibody detects endogenous levels of CSE1L.
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纯化方法
- The antibody was purified by protein G affinity chromatography.
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免疫原
- A synthetic peptide corresponding to the amino acid region 1 - 100 of the human Cellular Apoptosis Susceptibility/CSE1L protein.
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亚型
- IgG
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应用备注
- WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))
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别名
- Cellular Apoptosis Susceptibility/CSE1L
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背景
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Synonyms: CSE1L,CAS,XPO2,Exportin-2,Exp2,Cellular apoptosis susceptibility protein,Chromosome segregation 1-like protein,Importin-alpha re-exporter
Background: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],
Gene Name: CSE1L
Protein Name: Cellular Apoptosis Susceptibility/CSE1L
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基因ID
- 1434
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UniProt
- P55060
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途径
- Protein targeting to Nucleus
抗原
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