CRYAA 抗体 (AA 1-80)
Our Local Distributor
北京 101111
Quick Overview for CRYAA 抗体 (AA 1-80) (ABIN8120758)
抗原
See all CRYAA 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-80
-
原理
- CRYAA Antibody
-
特异性
- CRYAA Polyclonal Antibody detects endogenous levels of protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from human protein . at AA range: 1-80
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-2000 ELISA 1:5000-20000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- CRYAA (Crystallin, alpha A (CRYAA))
-
别名
- CRYAA
-
背景
-
Background: Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits, the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distin
Gene Name: CRYAA CRYA1 HSPB4
Protein Name: Alpha-crystallin A chain (Heat shock protein beta-4) (HspB4) [Cleaved into: Alpha-crystallin A chain, short form]
-
基因ID
- 1409
-
UniProt
- P02489
-
途径
- M Phase
抗原
-