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CRTC2 抗体

The 兔 多克隆 anti-CRTC2 antibody is suitable to detect CRTC2 in samples from 人, 大鼠 和 小鼠. It has been validated for WB.
产品编号 ABIN8120754
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CRTC2 抗体 (ABIN8120754)

抗原

See all CRTC2 抗体
CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

适用

  • 111
  • 29
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  • 2
  • 1
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  • 1
人, 大鼠, 小鼠

宿主

  • 102
  • 6
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  • 1
兔

克隆类型

  • 84
  • 29
多克隆

标记

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  • 2
  • 2
  • 1
  • 1
  • 1
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This CRTC2 antibody is un-conjugated

应用范围

  • 82
  • 38
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  • 7
  • 6
  • 5
  • 2
  • 1
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Western Blotting (WB)
  • 原理

    TORC2 Antibody

    特异性

    This antibody detects endogenous levels of TORC2 at Human, Mouse,Rat

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human TORC2

    亚型

    IgG
  • 应用备注

    WB 1:500-2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

    别名

    TORC2

    背景

    Synonyms: CREB-regulated transcription coactivator 2 (Transducer of regulated cAMP response element-binding protein 2) (TORC-2) (Transducer of CREB protein 2)

    Background: This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2010],

    Gene Name: CRTC2 TORC2

    Protein Name: TORC2

    基因ID

    200186

    UniProt

    Q53ET0

    途径

    AMPK Signaling, Carbohydrate Homeostasis
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