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C1RL 抗体 (AA 371-420)

This 兔 多克隆 antibody specifically detects C1RL in WB 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8120711
发货至: 中国
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Quick Overview for C1RL 抗体 (AA 371-420) (ABIN8120711)

抗原

See all C1RL 抗体
C1RL (Complement Component 1, R Subcomponent-Like (C1RL))

适用

  • 14
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 13
  • 1
  • 1
兔

克隆类型

  • 15
多克隆

标记

  • 10
  • 1
  • 1
  • 1
  • 1
  • 1
This C1RL antibody is un-conjugated

应用范围

  • 15
  • 9
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 371-420

    原理

    C1RL Antibody

    特异性

    C1RL Polyclonal Antibody detects endogenous levels of C1RL

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human C1RL. at AA range: 371-420

    亚型

    IgG
  • 应用备注

    WB 1:500-2000, ELISA 1:10000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    C1RL (Complement Component 1, R Subcomponent-Like (C1RL))

    别名

    C1RL

    背景

    Synonyms: Complement C1r subcomponent-like protein (C1r-LP) (C1r-like protein) (EC 3.4.21.-) (C1r-like serine protease analog protein) (CLSPa)

    Background: caution:Does not associate with the C1 complex. According to PubMed:15385675 doesn't cleave the proform of complement C1s.,function:Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.,induction:Up-regulated in monocytes and dendritic cells (DC) undergoing maturation or activation.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 CUB domain.,similarity:Contains 1 peptidase S1 domain.,tissue specificity:Highly expressed in placenta, liver, kidney, pancreas, moderately in lung, spleen, prostate, ovary, colon, and PBL, and weakly in heart, skeletal muscle, thymus, testis, and small intestine. Expressed in PC-3 (prostate adenocarcinoma) and SK-OV-3 (ovary adenocarcinoma) cells, but not in LoVo and HT-29 (colon adenocarcinoma), SMMC7721 (hepatocellular carcinoma), CaoV-3 (ovary adenocarcinoma), HeLa (cervix epithelioid carcinoma), MCF-7 (breast adenocarcinoma), U251 (glioma) or A549 (lung carcinoma) cells. Widely expressed in myeloid leukemia cell lines, including K-562 (chronic myelogenous leukemia), THP-1 (myelomonocytic leukemia), HL-60 and NB4 (promyelocytic leukemia), and KG-1 (acute myelogenous leukemia) cells. Expressed mainly in the liver and in serum (at protein level).,

    Gene Name: C1RL

    Protein Name: C1RL

    基因ID

    51279

    UniProt

    Q9NZP8
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