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Claudin 18 抗体 (AA 150-261)

The 小鼠 单克隆 anti-Claudin 18 antibody (Clone AB1310) (ABIN8120596) specifically detects Claudin 18 in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN8120596
发货至: 中国
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Quick Overview for Claudin 18 抗体 (AA 150-261) (ABIN8120596)

抗原

See all Claudin 18 (CLDN18) 抗体
Claudin 18 (CLDN18)

适用

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人

宿主

  • 42
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小鼠

克隆类型

  • 42
  • 11
单克隆

标记

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This Claudin 18 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

AB1310
  • 抗原表位

    • 13
    • 5
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    • 1
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    AA 150-261

    原理

    Claudin 18 Mouse mAb (Ready to Use)

    特异性

    The antibody can specifically recognize both human Claudin 18. 1 and Claudin 18. 2 protein.

    纯化方法

    The antibody was purified by protein G affinity chromatography.

    免疫原

    A synthetic peptide corresponding to the amino acid region 150 - 261 of the human Claudin 18 protein.

    亚型

    IgG
  • 应用备注

    It has been optimized for direct use, requiring no further dilution.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze

    储存条件

    4 °C

    储存方法

    Store at 4°C. Avoid freeze.
  • 抗原

    Claudin 18 (CLDN18)

    别名

    Claudin 18

    背景

    Synonyms: Claudin 18, Claudin-18, CLD18_HUMAN, CLDN18, SFTA5, SFTPJ

    Background: Claudin 18 is a 27 kDa membrane protein, belonging to the tight junction protein family. It is highly specifically expressed in gastric epithelial cells, and almost not expressed in other normal tissues. Studies have shown that the expression of gastric tissue increases after cancer, and the abnormal expression in pancreatic cancer, lung cancer, esophageal cancer and ovarian cancer promotes the metastasis of cancer cells. Therefore, antibody based drugs against Claudin 18 can significantly improve the survival rate of patients.

    Gene Name: CLDN18

    Protein Name: Claudin 18

    基因ID

    51208

    UniProt

    P56856

    途径

    Cell-Cell Junction Organization, Hepatitis C
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