Claudin 18 抗体 (AA 150-261)
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北京 101111
Quick Overview for Claudin 18 抗体 (AA 150-261) (ABIN8120596)
抗原
See all Claudin 18 (CLDN18) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 150-261
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原理
- Claudin 18 Mouse mAb (Ready to Use)
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特异性
- The antibody can specifically recognize both human Claudin 18. 1 and Claudin 18. 2 protein.
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纯化方法
- The antibody was purified by protein G affinity chromatography.
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免疫原
- A synthetic peptide corresponding to the amino acid region 150 - 261 of the human Claudin 18 protein.
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亚型
- IgG
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应用备注
- It has been optimized for direct use, requiring no further dilution.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze
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储存条件
- 4 °C
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储存方法
- Store at 4°C. Avoid freeze.
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- Claudin 18 (CLDN18)
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别名
- Claudin 18
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背景
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Synonyms: Claudin 18, Claudin-18, CLD18_HUMAN, CLDN18, SFTA5, SFTPJ
Background: Claudin 18 is a 27 kDa membrane protein, belonging to the tight junction protein family. It is highly specifically expressed in gastric epithelial cells, and almost not expressed in other normal tissues. Studies have shown that the expression of gastric tissue increases after cancer, and the abnormal expression in pancreatic cancer, lung cancer, esophageal cancer and ovarian cancer promotes the metastasis of cancer cells. Therefore, antibody based drugs against Claudin 18 can significantly improve the survival rate of patients.
Gene Name: CLDN18
Protein Name: Claudin 18
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基因ID
- 51208
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UniProt
- P56856
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途径
- Cell-Cell Junction Organization, Hepatitis C
抗原
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