C6orf150 抗体
Our Local Distributor
北京 101111
Quick Overview for C6orf150 抗体 (ABIN8120574)
抗原
See all C6orf150 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- cGAS Rabbit mAb
-
特异性
- This antibody detects endogenous levels of cGAS protein.
-
纯化方法
- The antibody was purified by protein A affinity chromatography.
-
免疫原
- Recombinant protein (or fragment).
-
亚型
- IgG
-
-
-
-
应用备注
- WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid freeze / thaw cycles
-
储存条件
- -20 °C
-
储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
-
-
- C6orf150 (Chromosome 6 Open Reading Frame 150 (C6orf150))
-
别名
- cGAS
-
背景
-
Synonyms: Protein MB21D1 (Mab-21 domain-containing protein 1)
Background: Enables several functions, including 2', 3'-cyclic GMP-AMP synthase activity, molecular condensate scaffold activity, and phosphatidylinositol-4, 5-bisphosphate binding activity. Involved in several processes, including defense response to symbiont, intracellular signal transduction, and regulation of defense response. Located in nuclear body, plasma membrane, and site of double-strand break. Is active in cytosol and nucleus. [provided by Alliance of Genome Resources, Feb 2025]
Gene Name: MB21D1 cGAS C6orf150
Protein Name: cGAS
-
基因ID
- 115004
-
UniProt
- Q8N884
-
途径
- Activation of Innate immune Response
抗原
-