CBX5 抗体
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北京 101111
Quick Overview for CBX5 抗体 (ABIN8120543)
抗原
See all CBX5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- HP1α Rabbit mAb
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特异性
- This antibody detects endogenous levels of HP1α protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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应用备注
- WB, 1:1000-1:5000 | IHC, 1:400-1:2000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- CBX5 (Chromobox Homolog 5 (CBX5))
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别名
- HP1alpha
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背景
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Synonyms: Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha)
Background: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008],
Gene Name: CBX5 HP1A
Protein Name: HP1α
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基因ID
- 23468
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UniProt
- P45973
抗原
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