CHRNA4 抗体 (AA 300-380)
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北京 101111
Quick Overview for CHRNA4 抗体 (AA 300-380) (ABIN8120527)
抗原
See all CHRNA4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 300-380
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原理
- ACHA4 Antibody
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特异性
- ACHA4 Polyclonal Antibody detects endogenous levels of protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human protein . at AA range: 300-380
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亚型
- IgG
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应用备注
- WB 1:500-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))
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别名
- ACHA4
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背景
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Background: This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012],
Gene Name: CHRNA4 NACRA4
Protein Name: Neuronal acetylcholine receptor subunit alpha-4
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基因ID
- 1137
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UniProt
- P43681
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途径
- Synaptic Membrane
抗原
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