CENPM 抗体 (AA 30-110)
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北京 101111
Quick Overview for CENPM 抗体 (AA 30-110) (ABIN8120458)
抗原
See all CENPM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-110
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原理
- CENP-M Antibody
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特异性
- This antibody detects endogenous levels of human CENP-M
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human CENP-M AA range: 30-110
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亚型
- IgG
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应用备注
- IHC 1:50-200, WB 1:500-2000. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CENPM (Centromere Protein M (CENPM))
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别名
- CENP-M
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背景
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Synonyms: Centromere protein M (CENP-M, Interphase centromere complex protein 39, Proliferation-associated nuclear element protein 1)
Background: The protein encoded by this gene is an inner protein of the kinetochore, the multi-protein complex that binds spindle microtubules to regulate chromosome segregation during cell division. It belongs to the constitutive centromere-associated network protein group, whose members interact with outer kinetochore proteins and help to maintain centromere identity at each cell division cycle. The protein is structurally related to GTPases but cannot bind guanosine triphosphate. A point mutation that affects interaction with another constitutive centromere-associated network protein, CENP-I, impairs kinetochore assembly and chromosome alignment, suggesting that it is required for kinetochore formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],
Gene Name: CENPM C22orf18 ICEN39 PANE1
Protein Name: CENP-M
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基因ID
- 79019
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UniProt
- Q9NSP4
抗原
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