Cathepsin D 抗体
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北京 101111
Quick Overview for Cathepsin D 抗体 (ABIN8120275)
抗原
See all Cathepsin D (CTSD) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Cathepsin D Antibody
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特异性
- Cathepsin D Polyclonal Antibody detects endogenous levels of Cathepsin D protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the Internal region of human Cathepsin D .
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Cathepsin D (CTSD)
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别名
- Cathepsin D
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背景
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Synonyms: CTSD; CPSD; Cathepsin D
Background: This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015],
Gene Name: CTSD
Protein Name: Cathepsin D
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基因ID
- 1509
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UniProt
- P07339
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途径
- Peptide Hormone Metabolism
抗原
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