CA9 抗体
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北京 101111
Quick Overview for CA9 抗体 (ABIN8120183)
抗原
See all CA9 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CA IX mouse mAb
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特异性
- The antibody can specifically recognize human CA IX protein.
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纯化方法
- The antibody was purified by affinity chromatography using a specific immunogen.
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免疫原
- Recombinant protein of the human CA IX protein.
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亚型
- IgG
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应用备注
- IHC, 1:200-1:400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- CA9 (Carbonic Anhydrase IX (CA9))
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别名
- CA IX
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背景
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Synonyms: G250, MN, Carbonic anhydrase 9, Carbonate dehydratase IX, Carbonic anhydrase IX, CA-IX, CAIX, Membrane antigen MN, P54/58N, Renal cell carcinoma-associated antigen G250, RCC-associated antigen G250, pMW1
Background: CA IX (Carbonic Anhydrase IX) is a transmembrane protein belonging to the carbonic anhydrase family. It catalyzes the conversion of carbon dioxide and water into bicarbonate and protons in the extracellular environment. CA IX is minimally expressed in normal tissues, primarily found in gastrointestinal epithelial cells, but is highly expressed in various malignant tumors, such as clear cell renal carcinoma, breast cancer, and pancreatic cancer. Its expression is significantly upregulated under hypoxic conditions. Therefore, CA IX has been widely studied as a tumor biomarker and a potential therapeutic target.
Gene Name: CA9
Protein Name: CA IX
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基因ID
- 768
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UniProt
- Q16790
抗原
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