Calreticulin 抗体
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北京 101111
Quick Overview for Calreticulin 抗体 (ABIN8120159)
抗原
See all Calreticulin (CALR) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Calreticulin Antibody
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特异性
- This antibody detects endogenous levels of human Calreticulin
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Recombinant Protein derived from human Calreticulin
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亚型
- IgG
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anti-Calreticulin (CALR) (AA 196-310) antibody
CALR 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Calreticulin (CALR) (AA 18-193) antibodyCALR 适用: 人 WB, IHC, FACS, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calreticulin (CALR) antibodyCALR 适用: 人, 小鼠 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 1G6A7 unconjugated
anti-Calreticulin (CALR) (AA 277-305) antibodyCALR 适用: 人, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21112 unconjugated
anti-Calreticulin (CALR) (AA 18-417) antibodyCALR 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7B3D7 unconjugated
anti-Calreticulin (CALR) antibodyCALR 适用: 人 WB, IHC, FACS, IP, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calreticulin (CALR) (AA 1-417) antibodyCALR 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G11-1A9 unconjugated
anti-Calreticulin (CALR) antibody (Atto 390)CALR 适用: 人 WB, IHC, FACS, IP, ICC, IF 宿主: 兔 Polyclonal Atto 390
anti-Calreticulin (CALR) antibody (Atto 488)CALR 适用: 人 WB, IHC, FACS, IP, ICC, IF 宿主: 兔 Polyclonal Atto 488
anti-Calreticulin (CALR) antibody (Atto 594)CALR 适用: 人 WB, IHC, FACS, IP, ICC, IF 宿主: 兔 Polyclonal Atto 594
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应用备注
- WB 1:500-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Calreticulin (CALR)
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别名
- Calreticulin
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背景
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Synonyms: Calreticulin (CRP55) (Calregulin) (Endoplasmic reticulum resident protein 60) (ERp60) (HACBP) (grp60)
Background: Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium. The amino terminus of calreticulin interacts with the DNA-binding domain of the glucocorticoid receptor and prevents the receptor from binding to its specific glucocorticoid response element. Calreticulin can inhibit the binding of androgen receptor to its
Gene Name: CALR CRTC
Protein Name: Calreticulin
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基因ID
- 811
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UniProt
- P27797
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途径
- Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response
抗原
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