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CAPN10 抗体

The 兔 多克隆 anti-CAPN10 antibody is suitable to detect CAPN10 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN8120148
发货至: 中国
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Quick Overview for CAPN10 抗体 (ABIN8120148)

抗原

See all CAPN10 抗体
CAPN10 (Calpain 10 (CAPN10))

适用

  • 22
  • 6
  • 3
  • 3
  • 3
  • 2
  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 24
兔

克隆类型

  • 24
多克隆

标记

  • 14
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This CAPN10 antibody is un-conjugated

应用范围

  • 13
  • 6
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA
  • 原理

    Calpain 10 Antibody

    特异性

    Calpain 10 Polyclonal Antibody detects endogenous levels of Calpain 10 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from the N-terminal region of human Calpain 10.

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    CAPN10 (Calpain 10 (CAPN10))

    别名

    Calpain 10

    背景

    Synonyms: CAPN10, KIAA1845, Calpain-10, Calcium-activated neutral proteinase 10, CANP 10

    Background: Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation, domain II, the protease domain, domain III, a linker domain of unknown function, and domain IV, the calmodulin-like calcium-binding domain.This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene. [provided by RefSeq,

    Gene Name: CAPN10

    Protein Name: Calpain-10

    基因ID

    11132

    UniProt

    Q9HC96

    途径

    Positive Regulation of Peptide Hormone Secretion
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