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BCCIP 抗体 (AA 60-140)

The 兔 多克隆 anti-BCCIP antibody (ABIN8120029) specifically detects BCCIP in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8120029
发货至: 中国
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Quick Overview for BCCIP 抗体 (AA 60-140) (ABIN8120029)

抗原

See all BCCIP 抗体
BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))

适用

人, 小鼠, 大鼠

宿主

  • 45
  • 5
兔

克隆类型

  • 49
  • 1
多克隆

标记

  • 25
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BCCIP antibody is un-conjugated

应用范围

  • 28
  • 21
  • 19
  • 16
  • 15
  • 14
  • 14
  • 11
  • 7
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 13
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 60-140

    原理

    TOK-1 Antibody

    特异性

    TOK-1 Polyclonal Antibody detects endogenous levels of TOK-1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from TOK-1 . at AA range: 60-140

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))

    别名

    TOK-1

    背景

    Synonyms: BCCIP, TOK1, BRCA2 and CDKN1A-interacting protein, P21- and CDK-associated protein 1, Protein TOK-1

    Background: This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

    Gene Name: BCCIP

    Protein Name: BRCA2 and CDKN1A-interacting protein

    基因ID

    56647

    UniProt

    Q9P287
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