Bestrophin 1 抗体 (AA 161-211)
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北京 101111
Quick Overview for Bestrophin 1 抗体 (AA 161-211) (ABIN8119984)
抗原
See all Bestrophin 1 (BEST1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 161-211
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原理
- Bestrophin-1 Antibody
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特异性
- The antibody detects endogenous Bestrophin-1 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthetic Peptide of Bestrophin-1 AA range: 161-211
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Bestrophin 1 (BEST1)
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别名
- Bestrophin-1
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背景
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Synonyms: Bestrophin-1 (TU15B, Vitelliform macular dystrophy protein 2)
Background: This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008],
Gene Name: BEST1
Protein Name: Bestrophin-1 (TU15B) (Vitelliform macular dystrophy protein 2)
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基因ID
- 7439
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UniProt
- O76090
抗原
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