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Bestrophin 1 抗体 (AA 161-211)

The 兔 多克隆 anti-Bestrophin 1 antibody (ABIN8119984) specifically detects Bestrophin 1 in WB, IHC 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8119984
发货至: 中国
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Quick Overview for Bestrophin 1 抗体 (AA 161-211) (ABIN8119984)

抗原

See all Bestrophin 1 (BEST1) 抗体
Bestrophin 1 (BEST1)

适用

  • 35
  • 17
  • 16
  • 2
  • 2
人, 小鼠, 大鼠

宿主

  • 45
  • 4
兔

克隆类型

  • 47
  • 2
多克隆

标记

  • 21
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Bestrophin 1 antibody is un-conjugated

应用范围

  • 41
  • 20
  • 10
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 13
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 161-211

    原理

    Bestrophin-1 Antibody

    特异性

    The antibody detects endogenous Bestrophin-1 protein

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthetic Peptide of Bestrophin-1 AA range: 161-211

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Bestrophin 1 (BEST1)

    别名

    Bestrophin-1

    背景

    Synonyms: Bestrophin-1 (TU15B, Vitelliform macular dystrophy protein 2)

    Background: This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008],

    Gene Name: BEST1

    Protein Name: Bestrophin-1 (TU15B) (Vitelliform macular dystrophy protein 2)

    基因ID

    7439

    UniProt

    O76090
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