BCL6 抗体 (acLys379)
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北京 101111
Quick Overview for BCL6 抗体 (acLys379) (ABIN8119947)
抗原
See all BCL6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- acLys379
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原理
- Bcl-6 (Acetyl Lys379) Antibody
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特异性
- This antibody detects endogenous levels of Human,Mouse,Rat Bcl-6 (Acetyl Lys379)
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human Bcl-6 (Acetyl Lys379)
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亚型
- IgG
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anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 501-600) antibody
BCL6 适用: 人 WB, IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 256-389) antibodyBCL6 适用: 人 ELISA 宿主: 小鼠 Monoclonal BCL6-1527 unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 147-276) antibodyBCL6 适用: 人 FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 2G1B6 unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (Internal Region) antibodyBCL6 适用: 人, 小鼠 WB, IHC (p), IP, ChIP 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (Internal Region) antibodyBCL6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 375-425) antibodyBCL6 适用: 人 IHC, WB, FACS, ICC, IP 宿主: 兔 Monoclonal BLR143H unconjugated Recombinant Antibody
anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 256-389) antibodyBCL6 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal BCL6-1982 unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 256-389) antibodyBCL6 适用: 人 WB 宿主: 小鼠 Monoclonal BCL6-1475 unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (Internal Region) antibodyBCL6 适用: 人, 大鼠 IHC, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 519-547), (C-Term) antibodyBCL6 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19464 unconjugated
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应用备注
- WB 1:1000-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
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别名
- Bcl-6
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背景
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Synonyms: B-cell lymphoma 6 protein (BCL-6, B-cell lymphoma 5 protein, BCL-5, Protein LAZ-3, Zinc finger and BTB domain-containing protein 27, Zinc finger protein 51)
Background: disease:A chromosomal aberration involving BCL6 may be a cause of a form of B-cell leukemia. Translocation t(3,11)(q27,q23) with POU2AF1/OBF1.,disease:A chromosomal aberration involving BCL6 may be a cause of lymphoma. Translocation t(3,4)(q27,p11) with ARHH/TTF.,disease:Chromosomal aberrations involving BCL6 may be a cause of B-cell non-Hodgkin lymphoma. Translocation t(3,14)(q27,q32), translocation t(3,22)(q27,q11) with immunoglobulin gene regions.,function:Transcriptional repressor which is required for germinal center formation and antibody affinity maturation. Probably plays an important role in lymphomagenesis.,induction:Down-regulated during maturation of dendritic cells by selective stimuli such as LPS, CD40L and zymosan.,PTM:Phosphorylated by MAPK1 in response to antigen receptor activation. Phosphorylation induces its degradation by ubiquitin/proteasome pathway.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 6 C2H2-type zinc fingers.,subunit:Interacts with ZBTB7 and BCL6B (By similarity). Interacts with the catalytic domain of HDAC9.,tissue specificity:Expressed in germinal center T and B cells and in primary immature dendritic cells.,
Gene Name: BCL6 BCL5 LAZ3 ZBTB27 ZNF51
Protein Name: Bcl-6 (Acetyl Lys379)
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基因ID
- 604
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UniProt
- P41182
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途径
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
抗原
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