ATR 抗体 (pThr1989)
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北京 101111
Quick Overview for ATR 抗体 (pThr1989) (ABIN8119902)
抗原
See all ATR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr1989
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原理
- ATR (Phospho Thr1989) Antibody
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特异性
- This antibody detects endogenous levels of Human ATR (phospho-Thr1989)
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized phosho peptide around human ATR (Thr1989)
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亚型
- IgG
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anti-ATR serine/threonine kinase (ATR) (AA 366-550) antibody
ATR 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3G6D2 unconjugated
anti-ATR serine/threonine kinase (ATR) (AA 2545-2645) antibodyATR 适用: 人 ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1E9 unconjugated
anti-ATR serine/threonine kinase (ATR) (pSer428) antibodyATR 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATR serine/threonine kinase (ATR) (AA 2545-2644) antibodyATR 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 3F2 unconjugated
anti-ATR serine/threonine kinase (ATR) (AA 2405-2644) antibodyATR 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATR serine/threonine kinase (ATR) (AA 1400-1500) antibodyATR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-ATR serine/threonine kinase (ATR) (AA 1675-1725) antibodyATR 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-ATR serine/threonine kinase (ATR) (AA 400-450) antibodyATR 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-ATR serine/threonine kinase (ATR) (pSer428) antibodyATR 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATR serine/threonine kinase (ATR) antibodyATR 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ATR (ATR serine/threonine kinase (ATR))
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别名
- ATR
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背景
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Synonyms: Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1)
Background: The protein encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1, checkpoint proteins RAD17, and RAD9, as well as tumor suppressor protein BRCA1. Mutations of this gene are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported, however, its full length nature is not known. Transcript variants utilizing alternative polyA sites exist. [provided by RefSeq, Jul 2008],
Gene Name: ATR FRP1
Protein Name: ATR (Thr1989)
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基因ID
- 545
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UniProt
- Q13535
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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