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ARNTL 抗体 (pSer42)

The 兔 多克隆 anti-ARNTL antibody (ABIN8119813) specifically detects ARNTL in WB. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN8119813
发货至: 中国
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Quick Overview for ARNTL 抗体 (pSer42) (ABIN8119813)

抗原

See all ARNTL 抗体
ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

适用

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人, 大鼠, 小鼠

宿主

  • 91
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兔

克隆类型

  • 85
  • 15
多克隆

标记

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This ARNTL antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    pSer42

    原理

    BMAL1 (Phospho Ser42) Antibody

    特异性

    This antibody detects endogenous levels of Human Mouse Rat BMAL1 (phospho-Ser42)

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

    免疫原

    Synthesized phosho peptide around human BMAL1 (Ser42)

    亚型

    IgG
  • 应用备注

    WB 1:1000-2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

    别名

    BMAL1

    背景

    Synonyms: Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Basic-helix-loop-helix-PAS protein MOP3) (Brain and muscle ARNT-like 1) (Class E basic helix-loop-helix protein 5) (bHLHe5) (Member of PAS protein 3) (PAS domain-containing protein 3) (bHLH-PAS protein JAP3)

    Background: The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],

    Gene Name: ARNTL BHLHE5 BMAL1 MOP3 PASD3

    Protein Name: BMAL1 (Ser42)

    基因ID

    406

    UniProt

    O00327

    途径

    Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Warburg Effect
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