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APITD1 抗体 (AA 70-150)

This 兔 多克隆 antibody specifically detects APITD1 in WB 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8119778
发货至: 中国
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Quick Overview for APITD1 抗体 (AA 70-150) (ABIN8119778)

抗原

See all APITD1 抗体
APITD1 (Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1))

适用

人, 小鼠, 大鼠

宿主

  • 12
  • 2
兔

克隆类型

  • 13
  • 1
多克隆

标记

  • 9
  • 1
  • 1
  • 1
  • 1
  • 1
This APITD1 antibody is un-conjugated

应用范围

  • 13
  • 9
  • 8
  • 8
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 70-150

    原理

    CENPS Antibody

    特异性

    CENPS Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human protein . at AA range: 70-150

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    APITD1 (Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1))

    别名

    CENPS

    背景

    Background: This gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF(II)31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes, including the Fanconi anemia (FA) core complex, the APITD1/CENPS complex, and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with chromatin associations of the FA core complex, and a role in the stable assembly of the outer kinetochore. Alternative splicing of this gene results in multiple transcript variants. Naturally occurring read-through transcripts also exist

    Gene Name: APITD1 CENPS FAAP16 MHF1

    Protein Name: Centromere protein S (CENP-S) (Apoptosis-inducing TAF9-like domain-containing protein 1) (FANCM-interacting histone fold protein 1) (Fanconi anemia-associated polypeptide of 16 kDa)

    基因ID

    100526739

    UniProt

    Q8N2Z9
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