APOB 抗体
Our Local Distributor
北京 101111
Quick Overview for APOB 抗体 (ABIN8119769)
抗原
See all APOB 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- APOB Antibody
-
特异性
- This antibody detects endogenous levels of Human APOB
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from human APOB
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:1000-2000 ELISA 1:5000-20000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- APOB (Apolipoprotein B (APOB))
-
别名
- APOB
-
背景
-
Synonyms: Apolipoprotein B-100 (Apo B-100) [Cleaved into: Apolipoprotein B-48 (Apo B-48)]
Background: This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008],
Gene Name: APOB
Protein Name: APOB
-
基因ID
- 338
-
UniProt
- P04114
-
途径
- Lipid Metabolism
抗原
-