beta 2 Adrenergic Receptor 抗体 (AA 300-380)
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Quick Overview for beta 2 Adrenergic Receptor 抗体 (AA 300-380) (ABIN8119731)
抗原
See all beta 2 Adrenergic Receptor (ADRB2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 300-380
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原理
- AR-β2 Antibody
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特异性
- AR-β2 Polyclonal Antibody detects endogenous levels of AR-β2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from AR-beta2 . at AA range: 300-380
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
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别名
- AR-beta2
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背景
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Synonyms: ADRB2, ADRB2R, B2AR, Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor
Background: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008],
Gene Name: ADRB2
Protein Name: Beta-2 adrenergic receptor
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基因ID
- 154
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UniProt
- P07550
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途径
- cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation
抗原
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