ALS2 抗体 (AA 390-470)
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Quick Overview for ALS2 抗体 (AA 390-470) (ABIN8119717)
抗原
See all ALS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 390-470
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原理
- ALS2 Antibody
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特异性
- ALS2 Polyclonal Antibody detects endogenous levels of protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human protein . at AA range: 390-470
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亚型
- IgG
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应用备注
- WB 1:500-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))
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别名
- ALS2
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背景
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Background: The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008],
Gene Name: ALS2 ALS2CR6 KIAA1563
Protein Name: Alsin (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein) (Amyotrophic lateral sclerosis 2 protein)
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基因ID
- 57679
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UniProt
- Q96Q42
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途径
- Skeletal Muscle Fiber Development
抗原
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