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ALS2 抗体 (AA 390-470)

The 兔 多克隆 anti-ALS2 antibody (ABIN8119717) specifically detects ALS2 in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8119717
发货至: 中国
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Quick Overview for ALS2 抗体 (AA 390-470) (ABIN8119717)

抗原

See all ALS2 抗体
ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))

适用

  • 44
  • 11
  • 6
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 39
  • 4
  • 1
兔

克隆类型

  • 40
  • 3
多克隆

标记

  • 24
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ALS2 antibody is un-conjugated

应用范围

  • 20
  • 13
  • 13
  • 10
  • 7
  • 5
  • 3
  • 3
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 390-470

    原理

    ALS2 Antibody

    特异性

    ALS2 Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human protein . at AA range: 390-470

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))

    别名

    ALS2

    背景

    Background: The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008],

    Gene Name: ALS2 ALS2CR6 KIAA1563

    Protein Name: Alsin (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein) (Amyotrophic lateral sclerosis 2 protein)

    基因ID

    57679

    UniProt

    Q96Q42

    途径

    Skeletal Muscle Fiber Development
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