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beta Amyloid 抗体

This 兔 多克隆 antibody specifically detects beta Amyloid in WB, IHC 和 IF. It exhibits reactivity toward 人 和 Hamster.
产品编号 ABIN8119709
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for beta Amyloid 抗体 (ABIN8119709)

抗原

See all beta Amyloid (Abeta) 抗体
beta Amyloid (Abeta) (Amyloid beta (Abeta))

适用

  • 91
  • 27
  • 20
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, Hamster

宿主

  • 51
  • 36
  • 2
  • 2
  • 2
兔

克隆类型

  • 55
  • 31
  • 3
多克隆

标记

  • 84
  • 5
  • 2
  • 1
  • 1
This beta Amyloid antibody is un-conjugated

应用范围

  • 50
  • 49
  • 45
  • 27
  • 21
  • 15
  • 9
  • 5
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 原理

    Amyloid-β Antibody

    特异性

    This antibody detects endogenous levels of human Amyloid-β

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human Amyloid-beta N-ternal

    亚型

    IgG
  • 应用备注

    IHC 1:50-200, WB 1:500-2000. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    beta Amyloid (Abeta) (Amyloid beta (Abeta))

    别名

    Amyloid-beta

    背景

    Synonyms: Amyloid beta A4 protein (ABPP, APPI, APP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP, PreA4, Protease nexin-II, PN-II) [Cleaved into: N-APP, Soluble APP-alpha (S-APP-alpha), Soluble APP-beta (S-APP-beta), C99, Beta-amyloid protein 42 (Beta-APP42), Beta-amyloid protein 40 (Beta-APP40), C83, P3(42), P3(40), C80, Gamma-secretase C-terminal fragment 59 (Amyloid intracellular domain 59, AICD-59, AID(59), Gamma-CTF(59)), Gamma-secretase C-terminal fragment 57 (Amyloid intracellular domain 57, AICD-57, AID(57), Gamma-CTF(57)), Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50, AICD-50, AID(50), Gamma-CTF(50)), C31]

    Background: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014],

    Gene Name: APP A4 AD1

    Protein Name: Amyloid beta A4 protein, Amyloid-β, Aβ

    基因ID

    351

    UniProt

    P05067

    途径

    Inflammasome
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