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Aminoacylase 1 抗体

The 兔 多克隆 anti-Aminoacylase 1 antibody is suitable to detect Aminoacylase 1 in samples from 人 和 小鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN8119701
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Aminoacylase 1 抗体 (ABIN8119701)

抗原

See all Aminoacylase 1 (ACY1) 抗体
Aminoacylase 1 (ACY1)

适用

  • 48
  • 28
  • 15
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 35
  • 13
  • 2
兔

克隆类型

  • 37
  • 13
多克隆

标记

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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Aminoacylase 1 antibody is un-conjugated

应用范围

  • 39
  • 25
  • 15
  • 13
  • 8
  • 7
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
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  • 1
Western Blotting (WB), ELISA
  • 原理

    ACY1 Antibody

    特异性

    ACY1 Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human protein

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Aminoacylase 1 (ACY1)

    别名

    ACY1

    背景

    Background: This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription als

    Gene Name: ACY1

    Protein Name: Aminoacylase-1 (ACY-1) (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase)

    基因ID

    95

    UniProt

    Q03154
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