alpha Tubulin 抗体 (acLys112)
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北京 101111
Quick Overview for alpha Tubulin 抗体 (acLys112) (ABIN8119671)
抗原
See all alpha Tubulin (TUBA1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- acLys112
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原理
- Tubulin α (Acetyl Lys112) Antibody
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特异性
- Acetyl-Tubulin α (K112) Polyclonal Antibody detects endogenous levels of Tubulin α protein only when acetylated at K112.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized acetyl-peptide derived from human Tubulin alpha around the acetylation site of K112.
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- alpha Tubulin (TUBA1)
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别名
- Tubulin alpha
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背景
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Synonyms: TUBA1A, TUBA3, Tubulin alpha-1A chain, Alpha-tubulin 3, Tubulin B-alpha-1, Tubulin alpha-3 chain, TUBA1B, Tubulin alpha-1B chain, Alpha-tubulin ubiquitousTubulin K-alpha-1, Tubulin alpha-ubiquitous chain, TUBA1C, TUBA6, Tubulin alpha-1C chain, Alpha-tubulin 6, Tubulin alpha-6 chain
Background: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species.This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.
Gene Name: TUBA1A/TUBA1B/TUBA1C
Protein Name: Tubulin alpha-1A chain/Tubulin alpha-1B chain/Tubulin alpha-1C chain
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基因ID
- 7846, 10376
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UniProt
- Q71U36
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途径
- Microtubule Dynamics
抗原
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