ASCC1 抗体 (AA 289-339)
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Quick Overview for ASCC1 抗体 (AA 289-339) (ABIN8119529)
抗原
See all ASCC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 289-339
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原理
- ASCC1 Antibody
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特异性
- This antibody detects endogenous levels of ASCC1 at Human/Mouse
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human ASCC1 AA range: 289-339
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亚型
- IgG
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应用备注
- WB 1:500-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ASCC1 (Activating Signal Cointegrator 1 Complex Subunit 1 (ASCC1))
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别名
- ASCC1
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背景
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Background: This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],
Gene Name: ASCC1 CGI-18
Protein Name: ASCC1
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基因ID
- 51008
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UniProt
- Q8N9N2
抗原
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