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Acetyl-CoA Carboxylase beta 抗体

The 兔 单克隆 anti-Acetyl-CoA Carboxylase beta antibody is suitable to detect Acetyl-CoA Carboxylase beta in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, ELISA, IP 和 IF.
产品编号 ABIN8119482
发货至: 中国
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中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Acetyl-CoA Carboxylase beta 抗体 (ABIN8119482)

抗原

See all Acetyl-CoA Carboxylase beta (ACACB) 抗体
Acetyl-CoA Carboxylase beta (ACACB)

适用

人, 小鼠, 大鼠

宿主

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兔

克隆类型

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单克隆

标记

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This Acetyl-CoA Carboxylase beta antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

克隆位点

AB2062
  • 原理

    ACACB Rabbit mAb

    特异性

    This antibody detects endogenous levels of ACACB protein.

    纯化方法

    The antibody was purified by protein A affinity chromatography.

    免疫原

    Recombinant protein (or fragment).

    亚型

    IgG
  • 应用备注

    WB, 1:2000-1:10000 | IHC, 1:1000-1:4000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    Acetyl-CoA Carboxylase beta (ACACB)

    别名

    ACACB

    背景

    Synonyms: ACC, ACAC, ACC1, ACCA, Acac1, hACC1, ACACAD, ACCalpha, ACACalpha

    Background: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008],

    Gene Name: ACACB ACC2 ACCB

    Protein Name: ACACB

    基因ID

    32

    UniProt

    O00763

    途径

    AMPK Signaling, Ribonucleoside Biosynthetic Process
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