Acetyl-CoA Carboxylase beta 抗体
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北京 101111
Quick Overview for Acetyl-CoA Carboxylase beta 抗体 (ABIN8119482)
抗原
See all Acetyl-CoA Carboxylase beta (ACACB) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- ACACB Rabbit mAb
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特异性
- This antibody detects endogenous levels of ACACB protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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应用备注
- WB, 1:2000-1:10000 | IHC, 1:1000-1:4000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- Acetyl-CoA Carboxylase beta (ACACB)
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别名
- ACACB
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背景
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Synonyms: ACC, ACAC, ACC1, ACCA, Acac1, hACC1, ACACAD, ACCalpha, ACACalpha
Background: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008],
Gene Name: ACACB ACC2 ACCB
Protein Name: ACACB
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基因ID
- 32
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UniProt
- O00763
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途径
- AMPK Signaling, Ribonucleoside Biosynthetic Process
抗原
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