Acetyl-CoA Carboxylase beta 抗体
Our Local Distributor
北京 101111
Quick Overview for Acetyl-CoA Carboxylase beta 抗体 (ABIN8119481)
抗原
See all Acetyl-CoA Carboxylase beta (ACACB) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- ACACB Antibody
-
特异性
- This antibody detects endogenous levels of ACACB at Human
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from human ACACB
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- Acetyl-CoA Carboxylase beta (ACACB)
-
别名
- ACACB
-
背景
-
Background: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008],
Gene Name: ACACB ACC2 ACCB
Protein Name: ACACB
-
基因ID
- 32
-
UniProt
- O00763
-
途径
- AMPK Signaling, Ribonucleoside Biosynthetic Process
抗原
-