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AIM2 抗体 (AA 255-354) (Cy5)

This Cy5-conjugated 兔 多克隆 anti-AIM2 antibody specifically detects AIM2 in WB, FACS, IF (cc) 和 IF (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN760770
发货至: 中国
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Quick Overview for AIM2 抗体 (AA 255-354) (Cy5) (ABIN760770)

抗原

See all AIM2 抗体
AIM2 (Absent in Melanoma 2 (AIM2))

适用

  • 70
  • 26
  • 18
  • 3
  • 3
  • 1
人, 小鼠, 大鼠

宿主

  • 60
  • 11
  • 2

克隆类型

  • 65
  • 8
多克隆

标记

  • 41
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This AIM2 antibody is conjugated to Cy5

应用范围

  • 59
  • 32
  • 29
  • 19
  • 12
  • 12
  • 12
  • 10
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 15
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 255-354

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from mouse AIM2

    亚型

    IgG
  • 应用备注

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    AIM2 (Absent in Melanoma 2 (AIM2))

    别名

    AIM2

    背景

    Synonyms: Gm1313, Ifi210, Interferon-inducible protein AIM2, Interferon-inducible protein 210, Ifi-210, Interferon-inducible protein p210, Aim2

    Background: Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8.

    基因ID

    383619

    UniProt

    Q91VJ1

    途径

    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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