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p107 抗体 (pThr369) (Biotin)

This anti-p107 antibody (ABIN760693) is a Rabbit Polyclonal antibody detecting p107 in WB, ELISA, IHC (p), IHC (fro). Suitable for Human.
产品编号 ABIN760693
发货至: 中国

Quick Overview for p107 抗体 (pThr369) (Biotin) (ABIN760693)

抗原

See all p107 (RBL1) 抗体
p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))

适用

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宿主

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克隆类型

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多克隆

标记

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This p107 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
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    pThr369

    交叉反应

    预测反应

    Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human p107 around the phosphorylation site of Thr369

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))

    别名

    p107

    背景

    Synonyms: RBL1phospho T369, 107 kDa retinoblastoma-associated protein, Cellular protein 107, Cellular protein p107, CP107, MGC40006, p107, PRB1, RBL1, RBL1_HUMAN, Retinoblastoma like protein 1, retinoblastoma-like 1 p107, Retinoblastoma-like protein 1.

    Background: p107 is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.

    基因ID

    5933

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases
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