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SMYD3 抗体 (AA 101-200) (Biotin)

This anti-SMYD3 antibody is a 兔 多克隆 antibody detecting SMYD3 in WB, ELISA, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN760588
发货至: 中国

Quick Overview for SMYD3 抗体 (AA 101-200) (Biotin) (ABIN760588)

抗原

See all SMYD3 抗体
SMYD3 (SET and MYND Domain Containing 3 (SMYD3))

适用

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宿主

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克隆类型

  • 45
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多克隆

标记

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This SMYD3 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 101-200

    交叉反应

    预测反应

    Mouse,Rat,Cow,Sheep,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human SMYD3

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    SMYD3 (SET and MYND Domain Containing 3 (SMYD3))

    别名

    SMYD3

    背景

    Synonyms: SET and MYND domain containing 3, SET and MYND domain containing protein 3, SMYD 3, SMYD3 protein, Zinc finger MYND domain containing 1, Zinc finger MYND domain containing protein 1, Zinc finger protein subfamily 3A MYND domain containing 1, ZMYND 1, ZMYND1, ZNFN3A1, SMYD3_HUMAN.

    Background: SMYD3 is a gene that is over-expressed in the majority of colorectal carcinomas and hepatocellular carcinomas. SMYD3 forms a complex with RNA polymerase II through an interaction with the RNA helicase HELZ and transactivates a set of genes that included oncogenes, homeobox genes and genes associated with cell-cycle regulation. SMYD3 binds to a motif, 5'-CCCTCC-3', present in the promoter region of downstream genes such as Nkx2.8. The SET domain of SMYD3 shows histone H3-lysine 4 (H3-K4)-specific methyltransferase activity, which is enhanced in the presence of the heat-shock protein HSP90A.

    基因ID

    64754
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