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PLAG1 抗体

This anti-PLAG1 antibody is a 兔 多克隆 antibody detecting PLAG1 in WB, IF (p) 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN760526
发货至: 中国

Quick Overview for PLAG1 抗体 (ABIN760526)

抗原

See all PLAG1 抗体
PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This PLAG1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human PLAG1

    亚型

    IgG
  • 应用备注

    WB 1:100-1000
    IHC-P 1:100-500
    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))

    别名

    Plag1

    背景

    Synonyms: PSA, SGPA, ZNF912, Zinc finger protein PLAG1, Pleiomorphic adenoma gene 1 protein, PLAG1

    Background: Transcription factor whose activation results in up-regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation: when overexpressed in cultured cells, higher proliferation rate and transformation are observed. Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction. Proto-oncogene whose ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas. Overexpression is associated with up-regulation of IGFII, is frequently observed in hepatoblastoma, common primary liver tumor in childhood. Cooperates with CBFB-MYH11, a fusion gene important for myeloid leukemia.

    基因ID

    5324

    UniProt

    Q6DJT9
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