SALL3 抗体 (N-Term)
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北京 101111
Quick Overview for SALL3 抗体 (N-Term) (ABIN8111107)
抗原
See all SALL3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- SALL3 Antibody - N-terminal region
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序列
- MSRRKQAKPQ HLKSDEELLP PDGAPEHAAP GEGAEDADSG PESRSGGEET
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预测反应
- Cow: 79%, Dog: 79%, Human: 100%, Mouse: 100%, Pig: 85%, Rat: 100%, Zebrafish: 93%
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SALL3
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39971-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- SALL3 (Sal-Like 3 (SALL3))
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别名
- SALL3
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背景
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Background Information: This gene encodes a sal-like C2H2-type zinc-finger protein, and belongs to a family of evolutionarily conserved genes found in species as diverse as Drosophila, C. elegans, and vertebrates. Mutations in some of these genes are associated with congenital disorders in human, suggesting their importance in embryonic development. This protein binds to DNA methyltransferase 3 alpha (DNMT3A), and reduces DNMT3A-mediated CpG island methylation. It is suggested that silencing of this gene, resulting in acceleration of DNA methylation, may have a role in oncogenesis.
Gene Name: spalt like transcription factor 3
Alternative Symbols: ZNF796
Protein Name: Sal-like protein 3
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分子量
- 143 kDa
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基因ID
- 27164
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NCBI登录号
- NP_741996
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UniProt
- Q9BXA9
抗原
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