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POMT1 抗体 (AA 651-747) (Cy7)

POMT1 适用: 人 IF (cc), IF (p) 宿主: 兔 Polyclonal Cy7
产品编号 ABIN760292
发货至: 中国
  • 抗原 See all POMT1 抗体
    POMT1 (Protein-O-Mannosyltransferase 1 (POMT1))
    抗原表位
    • 14
    • 10
    • 10
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 651-747
    适用
    • 42
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 43
    克隆类型
    • 43
    多克隆
    标记
    • 18
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POMT1 antibody is conjugated to Cy7
    应用范围
    • 29
    • 19
    • 17
    • 16
    • 12
    • 12
    • 7
    • 3
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Cow,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human POMT1
    亚型
    IgG
    Top Product
    Discover our top product POMT1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    POMT1 (Protein-O-Mannosyltransferase 1 (POMT1))
    别名
    POMT1 (POMT1 产品)
    别名
    LGMD2K antibody, MDDGA1 antibody, MDDGB1 antibody, MDDGC1 antibody, RT antibody, AI505244 antibody, protein O-mannosyltransferase 1 antibody, protein-O-mannosyltransferase 1 antibody, POMT1 antibody, Pomt1 antibody
    背景

    Synonyms: POMT1_HUMAN, Protein O-mannosyl-transferase 1, Dolichyl-phosphate-mannose--protein mannosyltransferase 1.

    Background: POMT1 (Protein O mannosyl transferase 1) is a multipass membrane protein that is found in the endoplasmic reticulum. POMT1 catalyses the transfer of mannosyl residues to the hydroxyl groups of serine or threonine residues. Enzymatic activity is dependent on co expression of POMT1 with POMT2. Defects in the POMT1 gene are associated with Walker-Warburg syndrome (WWS), a congential muscular dystrophy that is associated with mental retardation and is usually lethal within the first few months of life. Other defects in the POMT1 gene result in limb girdle muscular dystrophy type 2K (LGMD2K), which is associated with mild mental retardation. Studies in Drosophila suggest that mutation of POMT1 alters the efficacy of synaptic transmission and a change in subunit composition of post synaptic glutamate receptors at the neuromuscular junction. Missense mutations in POMT1 have been associated with glioneuronal and glial brain tumours.

    基因ID
    10585
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