PRDM12 抗体 (C-Term)
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北京 101111
Quick Overview for PRDM12 抗体 (C-Term) (ABIN8108788)
抗原
See all PRDM12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- PRDM12 Antibody - C-terminal region
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序列
- IPGVPGLEED QKKNKHEDFH PADSAAGPAG RMRCVICHRG FNSRSNLRSH
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human PRD12
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33217-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PRDM12 (PR Domain Containing 12 (PRDM12))
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别名
- PRDM12
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背景
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Background Information: This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN's) affecting peripheral sensory and autonomic neurons. Deregulation of this gene is associated with solid cancers and hematological malignancies including chronic myeloid leukaemia.
Gene Name: PR/SET domain 12
Alternative Symbols: PFM9, HSAN8
Protein Name: PR domain zinc finger protein 12
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分子量
- 40kDa
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基因ID
- 59335
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NCBI登录号
- NP_067632
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UniProt
- Q9H4Q4
抗原
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